FaCD Online Syndrome Fact Sheet

Last updated: 19 Oct 2009

Name: Carcinoma of Sebacous Gland, Thyroid and Breast

Mode of Inheritance: ?

Tumor features

breast tumor
sebaceous carcinoma
thyroid cancer, papillary


Newman et al[1] reported a 52-year-old Caucasian woman diagnosed with sebaceous gland carcinoma of the eyelid, followed by breast cancer and papillary carcinoma of the thyroid. There was a history of radiation exposure. Testing for most likely candidates such as Muir-Torre and Cowden syndrome proved negative. The authors suggested that their patients disorder represented a novel cancer susceptibility disorder or a variant of the Muir-Torre syndrome.


[1] Newman BD, Maher JF, Subauste JS, Uwaifo GI, Bigler SA, Koch CA. Clustering of sebaceous gland carcinoma, papillary thyroid carcinoma and breast cancer in a woman as a new cancer susceptibility disorder: a case report. J Med Case Reports. 2009 Jul 16;3:6905